Hemolysin as a Virulence Factor for Systemic Infection with Isolates of Mycobacterium avium Complex
نویسندگان
چکیده
منابع مشابه
Most human isolates of Mycobacterium avium Mav-A and Mav-B are strong producers of hemolysin, a putative virulence factor.
Hemolysin was quantified in 58 isolates of Mycobacterium avium from human, animal, and environmental sources. Human Mav-A and Mav-B isolates were the strongest producers; in contrast, animal and environmental Mav-A isolates and human, animal, and environmental Mav-C organisms were low-level producers. Hemolysin production was not restricted to isolates causing invasive infections.
متن کاملEnvironmental risk factors for infection with Mycobacterium avium complex.
Infection with Mycobacterium avium complex is acquired from the environment, but risk factors for M. avium complex infection and disease are poorly understood. To identify risk factors for infection, the authors performed a 1998-2000 cross-sectional study in western Palm Beach County, Florida, using a population-based random household survey. M. avium complex infection was identified by use of ...
متن کاملMycobacterium avium complex infection: phenotypes and outcomes.
Nontuberculous mycobacteria (NTM) pulmonary disease is becoming increasingly recognised as an emerging healthcare issue. Multiple studies have demonstrated an increasing prevalence throughout the world, with evidence of significant associated morbidity, mortality and healthcare costs [1, 2]. The most prevalent and important group leading to pulmonary disease is the Mycobacterium avium complex (...
متن کاملConsolidations in Nodular Bronchiectatic Mycobacterium Avium Complex Lung Disease: Mycobacterium Avium Complex or Other Infection?
PURPOSE The objective of this study is to define the clinical implications of consolidations in nodular bronchiectatic type Mycobacterium avium complex (NBMAC) infection. MATERIALS AND METHODS A total of 69 patients (M : F = 17 : 52; mean age, 64 years; age range, 41-85 years) with MAC isolated in the sputum culture and nodular bronchiectasis on the initial and follow-up CT scans were include...
متن کاملPulmonary Mycobacterium avium complex infection: association with NRAMP1 polymorphisms.
The present study aimed to elucidate risk factors for nonimmunocompromised pulmonary Mycobacterium avium complex (MAC) infection. Epidemiological data and variations of candidate genes for mycobacterial diseases were analysed in 111 patients with pulmonary MAC infection. Four polymorphisms of the human natural resistance-associated macrophage protein (NRAMP)1 gene, the 5'(GT)n, 469+14 G/C, D543...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1999
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.37.2.445-446.1999